"Lorenzo is going to be out for the next three months which is obviously a major blow to us," Rovers boss Graeme Souness told the Lancashire Evening Telegraph.
"They had a look at his knee and discovered that he's suffering from a similar sort of problem to Craig Short.
"They had to scrape away some of the bone in his knee which helps to promote new growth.
"But we are looking at the New Year before he's going to be ready again which is disappointing."